L-5-MTHF - METHYLATED FOLATE

L-5-MTHF provides the biologically active form of folate to support folate status and promote normal methylation and homocysteine metabolism. It delivers folate as 5-methyltetrahydrofolate (5-MTHF)—the bioidentical, active circulating form found in the body and in foods. This product features Quatrefolic® (a patented glucosamine-salt form) for high bioavailability, solubility, and stability. Designs for Health offers a 1,000 mcg strength to accommodate individualized supplementation.

How it works:
Folate is required for DNA synthesis and repair, red blood cell formation, and normal methylation—processes that influence cardiovascular, neurological, detoxification, and reproductive function. Unlike folic acid (which requires multiple conversion steps), 5-MTHF arrives in the active form. Individuals with certain genetic variations may have reduced capacity to convert folic acid; providing 5-MTHF supports efficient methylation and homocysteine metabolism.

Benefits:
• Helps to form red blood cells
• Helps prevent folate deficiency
• Helps support the body’s ability to metabolize nutrients
• Helps reduce the risk of neural tube defects when taken daily at least three months prior to becoming pregnant and during early pregnancy
• Helps support normal early fetal development (brain and spinal cord)

Highlights
• Bioactive folate as Quatrefolic® [6S]-5-MTHF to support folate status and methylation
• Patented glucosamine-salt form (not calcium salt) for increased bioavailability and stability
• 1,000 mcg per capsule

Recommended dose:
Adults: Take 1 capsule per day, or as directed by your health-care practitioner. Consult a health-care practitioner for use beyond 12 weeks.

Notes:
• High folate intake may mask vitamin B12 deficiency and its related anemia; consider assessing B12 status, especially with long-term use or higher doses.
• Always consult your health-care practitioner about your specific circumstances and any questions you have.